Group Meal November 2018

Ayla, Amanda, Richard, Alex

Christmas 2017 with the Campopiano group

L-R, B: Stacey, Alex, Pete, Alexis, Van, Ben, Jo, Annabel, Dom.

L-R, F: Piera, Amanda, Fengxin, Silvia, Gary, Yanik

Dr Amanda Jarvis

Amanda obtained her MChem from the University of St Andrews (UK) and received a PhD from the University of York (UK).  After this she conducted postdoctoral research in the Dauban group (ICSN, Gif-sur-Yvette) and the Kamer group (St Andrews, UK). In 2015, she received a Marie Curie Individual Fellowship to continue working in Prof. Paul Kamer’s group on Artificial Metalloenzymes for the Oxidation of Alkanes (ArtOxiZymes). In 2017 she started her independent career as a Christina Miller Fellow at the University of Edinburgh, and has recently been awarded a UKRI Future Leaders Fellowship.

Present members

Eva Klemencic, PhD student

Eva graduated with a Bachelor's degree in Biochemistry at the University of Ljubljana, Slovenia. She joined the School of Chemistry at the University of Edinburgh to work with Amanda  on artificial metalloenzymes as part of her project work for MSc in Biochemistry. Her research focused on incorporation of unnatural amino acids that can bind metals into the protein scaffold and screening for the biocatalytic activities of these novel artificial metalloenzymes. She has returned to the School of Chemistry for a PhD with Amanda Jarvis, where she continues to work on the design of artificial metalloenyzmes.

Dr Richard Brewster, Postdoc

Richard graduated with an MChem from the University of Edinburgh with industrial experience in medicinal chemistry at UCB in Belgium. His PhD work with Prof. Alison Hulme focused on the design and synthesis of novel cysteine targeting protein post-translational modification mimics. He moved to the School of Biological Sciences for a year to work with Dr Stephen Wallace investigating whole cell catalysis reactions in E. coli before returning to the School of Chemisty to work with Dr Amanda Jarvis. His research interests will look at incorporating unnatural amino acids into protein scaffolds and screening their potential for metal binding and catalysis.

Dan Edwards, PhD

Dan graduated with an MChem from the University of Lincoln, awarded the Bruker and BASF prize for best performance in chemistry. He recently completed an industrial research project establishing protocols for the manufacture and analysis of PEGylated protein therapeutics within regulated clinical studies, at Intertek Pharmaceutical Services Manchester. He joined the School of Chemistry at the University of Edinburgh in a collaborative research project with Dr Amanda Jarvis and Professor Scott Cockroft, supported by funding from EASTBIO. His PhD project aims to develop catalytically active transmembrane protein nanopores for applications in mechanistic elucidation and biochemical flow systems

Alumni

Ruburika Nagao, Summer Student, 2019

Ayla de Heney, MChem Student. 2018-2019

Alexander Daniels, Visiting student from Haverford College, 2018

Marie Jadoul, Erasmus student from Ensicaen, 2018

Paul Rooney, MChem Student 2017-2018

Yanik Becker, Erasmus Student from the University of Kaiserslautern, 2017 (Currently a PhD student with Professor Thiel, University of Kaiserslautern)

Matthew Vaughan, MChem

Matthew is currently pursuing a Master’s degree in chemistry from the University of Edinburgh.  He joined the ‘New Synthetic Methods’ group at the University of Connecticut, USA, as part of a year abroad program to gain research experience. He worked on the photocatalysed oxidation of primary amines to activated amides.  Currently he is working with Dr Amanda Jarvis as part of his MChem research project, which involves the synthesis and incorporation of unnatural amino acids into protein scaffolds being developed for metalloenzyme catalysis.

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